ea0037ep58 | Adrenal cortex | ECE2015
Wester Vincent L
, Koper Jan W
, van den Akker Erica L T
, de Rijke Yolanda B
, Manenschijn Laura
, Feelders Richard A
, van Rossum Elisabeth F C
Background: Endogenous Cushings syndrome (CS) is caused by overproduction of cortisol. Current first-line screening tests for CS can produce false positive results due to medication use and stress, rely heavily on patient adherence to sampling instructions, and only measure short-term cortisol exposure which limits sensitivity. In general multiple tests are required to establish a diagnosis. Hair cortisol concentrations (HCC) offer a minimally invasive way to measure lon...